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Glucose kinetics and exercise tolerance in mice lacking the GLUT4 glucose transporter

The absence of GLUT4 severely impairs basal glucose uptake in vivo, but does not alter glucose homeostasis or circulating insulin. Glucose uptake in isolated contracting skeletal muscle (MGU) is also impaired by the absence of GLUT4, and onset of muscle fatigue is hastened. Whether the body can comp...

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Autores principales: Fueger, Patrick T, Li, Candice Y, Ayala, Julio E, Shearer, Jane, Bracy, Deanna P, Charron, Maureen J, Rottman, Jeffrey N, Wasserman, David H
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075340/
https://ncbi.nlm.nih.gov/pubmed/17495042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.132902
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