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Disinhibition of perifornical hypothalamic neurones activates noradrenergic neurones and blocks pontine carbachol-induced REM sleep-like episodes in rats

Studies in behaving animals suggest that neurones located in the perifornical (PF) region of the posterior hypothalamus promote wakefulness and suppress sleep. Among such cells are those that synthesize the excitatory peptides, orexins (ORX). Lack of ORX, or their receptors, is associated with narco...

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Detalhes bibliográficos
Main Authors: Lu, Jackie W, Fenik, Victor B, Branconi, Jennifer L, Mann, Graziella L, Rukhadze, Irma, Kubin, Leszek
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075326/
https://ncbi.nlm.nih.gov/pubmed/17495048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.127613
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