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Membrane cholesterol modulates Kv1.5 potassium channel distribution and function in rat cardiomyocytes

Membrane lipid composition is a major determinant of cell excitability. In this study, we assessed the role of membrane cholesterol composition in the distribution and function of Kv1.5-based channels in rat cardiac membranes. In isolated rat atrial myocytes, the application of methyl-β-cyclodextrin...

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Main Authors: Abi-Char, Joëlle, Maguy, Ange, Coulombe, Alain, Balse, Elise, Ratajczak, Philippe, Samuel, Jane-Lise, Nattel, Stanley, Hatem, Stéphane N
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075263/
https://ncbi.nlm.nih.gov/pubmed/17525113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.134809
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