Single-base mutations at position 2661 of Escherichia coli 23S rRNA increase efficiency of translational proofreading.

Two single-base substitutions were constructed in the 2660 loop of Escherichia coli 23S rRNA (G2661-->C or U) and were introduced into the rrnB operon cloned in plasmid pKK3535. Ribosomes were isolated from bacteria transformed with the mutated plasmids and assayed in vitro in a poly(U)-directed sys...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Melançon, P, Tapprich, W E, Brakier-Gingras, L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207523/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1281147/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.174.24.7896-7901.1992
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