Synaptic modifications at the CA3–CA1 synapse after chronic AMPA receptor blockade in rat hippocampal slices

Maintenance of dendritic spines, the postsynaptic elements of most glutamatergic synapses in the central nervous system, requires continued activation of AMPA receptors. In organotypic hippocampal slice cultures, chronic blockade of AMPA receptors for 14 days induces a substantial loss of dendritic...

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Bibliografiska uppgifter
Huvudupphovsmän: Mateos, José María, Lüthi, Andreas, Savic, Natasa, Stierli, Beat, Streit, Peter, Gähwiler, Beat H, McKinney, R Anne
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 2007
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075211/
https://ncbi.nlm.nih.gov/pubmed/17303644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.120550
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