Levofloxacin Pharmacokinetics in Adult Cystic Fibrosis

BACKGROUND: Cystic fibrosis (CF) patients have enhanced renal clearance of aminoglycosides and several β-lactams and require higher dosages. Levofloxacin is a fluoroquinolone with extensive renal elimination and enhanced penetration into lungs and Pseudomonas aeruginosa (PA) biofilms. We studied the...

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Main Authors: Lee, Carlton K. K., Boyle, Michael P., Diener-West, Marie, Brass-Ernst, Lois, Noschese, Michelle, Zeitlin, Pamela L.
格式: Artigo
語言:Inglês
出版: 2007
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075103/
https://ncbi.nlm.nih.gov/pubmed/17356095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1378/chest.06-1524
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