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Dissection and Modulation of the Four Distinct Activities of Nisin by Mutagenesis of Rings A and B and by C-Terminal Truncation

Nisin A is a pentacyclic antibiotic peptide produced by various Lactococcus lactis strains. Nisin displays four different activities: (i) it autoinduces its own synthesis; (ii) it inhibits the growth of target bacteria by membrane pore formation; (iii) it inhibits bacterial growth by interfering wit...

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Détails bibliographiques
Auteurs principaux: Rink, Rick, Wierenga, Jenny, Kuipers, Anneke, Kluskens, Leon D., Driessen, Arnold J. M., Kuipers, Oscar P., Moll, Gert N.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074915/
https://ncbi.nlm.nih.gov/pubmed/17660303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01104-07
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