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Directed Evolution of Vibrio fischeri LuxR for Improved Response to Butanoyl-Homoserine Lactone

LuxR is the 3-oxohexanoyl-homoserine lactone (3OC6HSL)-dependent transcriptional activator of the prototypical acyl-homoserine lactone (AHL) quorum-sensing system of Vibrio fischeri. Wild-type LuxR exhibits no response to butanoyl-HSL (C4HSL) in quantitative bioassays at concentrations of up to 1 μM...

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Detalhes bibliográficos
Main Authors: Hawkins, Andrew C., Arnold, Frances H., Stuermer, Rainer, Hauer, Bernhard, Leadbetter, Jared R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074898/
https://ncbi.nlm.nih.gov/pubmed/17675429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00060-07
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