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Live Imaging of Neuronal Connections by Magnetic Resonance: Robust Transport in the Hippocampal-Septal Memory Circuit in a Mouse Model of Down Syndrome
Connections from hippocampus to septal nuclei have been implicated in memory loss and the cognitive impairment in Down syndrome (DS). We trace these connections in living mice by Mn(2+) enhanced 3D MRI and compare normal with a trisomic mouse model of DS, Ts65Dn. After injection of 4 nl of 200 mM Mn...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2074885/ https://ncbi.nlm.nih.gov/pubmed/17566763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2007.05.010 |
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