Acceleration of MRP-associated efflux of rhodamine 123 by genistein and related compounds.

Multidrug resistance (MDR), caused by overexpression of either P-glycoprotein or the multidrug resistance protein (MRP), is characterised by a decreased cellular drug accumulation due to an enhanced drug efflux. In this study, we examined the effects of genistein and structurally related (iso)flavon...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Versantvoort, C. H., Rhodes, T., Twentyman, P. R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 1996
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074826/
https://ncbi.nlm.nih.gov/pubmed/8980395
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