Synergistic effects of TNF-alpha and melphalan in an isolated limb perfusion model of rat sarcoma: a histopathological, immunohistochemical and electron microscopical study.

Isolated limb perfusion (ILP) with tumour necrosis factor alpha (TNF-alpha) and melphalan has shown impressive results in patients with irresectable soft tissue sarcomas and stage III melanoma of the extremities. The mechanisms of the reported in vivo synergistic anti-tumour effects of TNF-alpha and...

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Main Authors: Nooijen, P. T., Manusama, E. R., Eggermont, A. M., Schalkwijk, L., Stavast, J., Marquet, R. L., de Waal, R. M., Ruiter, D. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074822/
https://ncbi.nlm.nih.gov/pubmed/8980389
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