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Overexpression of the ABC transporter TAP in multidrug-resistant human cancer cell lines.

Multidrug resistance (MDR) to anti-cancer drugs has been associated with the overexpression of P-glycoprotein (P-gp) and the multidrug resistance-associated protein (MRP), both being members of the ATP-binding cassette (ABC) superfamily of transporters. We investigated whether in addition to P-gp an...

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Autors principals: Izquierdo, M. A., Neefjes, J. J., Mathari, A. E., Flens, M. J., Scheffer, G. L., Scheper, R. J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074820/
https://ncbi.nlm.nih.gov/pubmed/8980397
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