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Reduced capacity of tumour blood vessels to produce endothelium-derived relaxing factor: significance for blood flow modification.

The effect of nitric oxide-dependent vasodilators on vascular resistance of tumours and normal tissue was determined with the aim of modifying tumour blood flow for therapeutic benefit. Isolated preparations of the rat P22 tumour and normal rat hindlimb were perfused ex vivo. The effects on tissue v...

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Detalhes bibliográficos
Main Authors: Tozer, G. M., Prise, V. E., Bell, K. M., Dennis, M. F., Stratford, M. R., Chaplin, D. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074803/
https://ncbi.nlm.nih.gov/pubmed/8980396
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