Therapeutic activity of CPT-11, a DNA-topoisomerase I inhibitor, against peripheral primitive neuroectodermal tumour and neuroblastoma xenografts.

The anti-tumour activity of CPT-11, a topoisomerase I inhibitor, was evaluated in four human neural-crest-derived paediatric tumour xenografts; one peripheral primitive neuroectodermal tumour (pPNET) (SK-N-MC) and three neuroblastomas. Two models, SK-N-MC and IGR-N835, were established in athymic mi...

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Bibliographic Details
Main Authors:	Vassal, G., Terrier-Lacombe, M. J., Bissery, M. C., Vénuat, A. M., Gyergyay, F., Bénard, J., Morizet, J., Boland, I., Ardouin, P., Bressac-de-Paillerets, B., Gouyette, A.
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 1996
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2074686/ https://ncbi.nlm.nih.gov/pubmed/8761367
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Therapeutic activity of CPT-11, a DNA-topoisomerase I inhibitor, against peripheral primitive neuroectodermal tumour and neuroblastoma xenografts.

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