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Receptor-mediated uptake of low-density lipoprotein by B16 melanoma cells in vitro and in vivo in mice.

Selective delivery of cytotoxic anti-neoplastic drugs can diminish the severe side-effects associated with these drugs. Many malignant tumours express high levels of low-density lipoprotein (LDL) receptors on their membranes. Therefore, LDL may be used as a carrier to obtain selective delivery of an...

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Detalhes bibliográficos
Main Authors: Versluis, A. J., van Geel, P. J., Oppelaar, H., van Berkel, T. J., Bijsterbosch, M. K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074664/
https://ncbi.nlm.nih.gov/pubmed/8761365
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