DNA damage and repair in tumour and non-tumour tissues of mice induced by nicotinamide.

In vivo DNA damage and repair was induced by nicotinamide (NAM) in adenotype 12 virus-induced mouse sarcoma A12B3 and sarcoma F inoculated into CBA mice. DNA damage, NAM and NAD concentrations were measured after in vivo exposure to NAM, in tumours and spleens by alkaline elution and by HPLC analysi...

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Главные авторы: Olsson, A. R., Sheng, Y., Pero, R. W., Chaplin, D. J., Horsman, M. R.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 1996
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074637/
https://ncbi.nlm.nih.gov/pubmed/8695350
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