The relationship between tumour glutathione concentration, glutathione S-transferase isoenzyme expression and response to single agent carboplatin in epithelial ovarian cancer patients.

There is evidence to suggest that glutathione (GSH) and glutathione-S-transferases (GST) are important factors in determining sensitivity to cytotoxic drugs in vitro and in preclinical in vivo model systems. To define the relationship between tumour GSH concentration, GST isoenzyme expression and re...

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Autors principals: Ghazal-Aswad, S., Hogarth, L., Hall, A. G., George, M., Sinha, D. P., Lind, M., Calvert, A. H., Sunter, J. P., Newell, D. R.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074632/
https://ncbi.nlm.nih.gov/pubmed/8695367
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