Relationship between the exposure to cisplatin, DNA-adduct formation in leucocytes and tumour response in patients with solid tumours.

The study was designed to investigate possible relationships between tumour response and exposure to cisplatin (area under the curve of unbound cisplatin in plasma, AUC) and DNA-adduct formation in leucocytes (WBC) in patients with solid tumours. Patients were treated with six weekly courses of cisp...

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Main Authors: Schellens, J. H., Ma, J., Planting, A. S., van der Burg, M. E., van Meerten, E., de Boer-Dennert, M., Schmitz, P. I., Stoter, G., Verweij, J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074557/
https://ncbi.nlm.nih.gov/pubmed/8664132
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