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Different biodistribution of 99mTc-labelled chimeric mouse-human monoclonal antibody between athymic mice model and human.

Biodistribution of chimeric mouse/human monoclonal antibody against non-specific cross-reacting antigen (chNCA Ab) was studied in athymic mice and patients with metastatic bone disease. 99mTc-chNCA Ab showed a high labelling efficiency, stability and also a high binding ratio to human granulocytes....

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Autors principals: Oriuchi, N., Watanabe, N., Sugiyama, S., Higuchi, T., Imai, K., Yamanaka, H., Hashimoto, M., Kanda, H., Endo, K.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074533/
https://ncbi.nlm.nih.gov/pubmed/8664114
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