Effect of transfection of a Drosophila topoisomerase II gene into a human brain tumour cell line intrinsically resistant to etoposide.

The human brain tumour cell line HBT20 is intrinsically resistant to etoposide and does not express mdr-1 mRNA. These studies were conducted to determine whether transfecting a Drosophila (D) topoisomerase II (topo II) gene into HBT20 cells could increase their sensitivity to etoposide. A D-topo II...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Asano, T., Zwelling, L. A., An, T., McWatters, A., Herzog, C. E., Mayes, J., Loughlin, S. M., Kleinerman, E. S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 1996
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074495/
https://ncbi.nlm.nih.gov/pubmed/8645582
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk