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High frequency of chromosome 9 deletion in ovarian cancer: evidence for three tumour-suppressor loci.

We have screened 33 ovarian tumours of various grades and stages for the loss of heterozygosity (LOH) of markers on chromosome 9. LOH was detected in 26 cases (79%). Eleven tumours (33%) showed LOH of all informative markers. The remaining 15 cases had partial deletions. Of these, six (18%) had loss...

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Détails bibliographiques
Auteurs principaux: Devlin, J., Elder, P. A., Gabra, H., Steel, C. M., Knowles, M. A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074458/
https://ncbi.nlm.nih.gov/pubmed/8595153
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