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The nuclear matrix revealed by eluting chromatin from a cross-linked nucleus

The nucleus is an intricately structured integration of many functional domains whose complex spatial organization is maintained by a nonchromatin scaffolding, the nuclear matrix. We report here a method for preparing the nuclear matrix with improved preservation of ultrastructure. After the removal...

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Autori principali: Nickerson, Jeffrey A., Krockmalnic, Gabriela, Wan, Katherine M., Penman, Sheldon
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC20742/
https://ncbi.nlm.nih.gov/pubmed/9114009
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