Intracellular activation of gelatinase A (72-kDa type IV collagenase) by normal fibroblasts

Normal fibroblasts cultured as monolayers secrete matrix metalloproteinases (MMP), including gelatinase A (72-kDa type IV collagenase) as inactive zymogens. Previously we found that normal fibroblasts cultured in a type I collagen lattice (dermal equivalent) secrete active gelatinase A. Here we show...

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Main Authors: Lee, Ai Young, Akers, Kathryn T., Collier, Mitchell, Li, Lin, Eisen, Arthur Z., Seltzer, Jo Louise
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences of the USA 1997
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC20738/
https://ncbi.nlm.nih.gov/pubmed/9114005
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