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The bovine papillomavirus E6 oncoprotein interacts with paxillin and disrupts the actin cytoskeleton

The E6 oncoprotein of bovine papillomavirus type 1 (BPV-1) has been shown to transform cells through a p53-independent pathway, but its transforming mechanism is unknown. Here we demonstrate in vitro and in vivo interactions between BPV-1 E6 and the focal adhesion protein paxillin. The ability of BP...

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Detalhes bibliográficos
Main Authors: Tong, Xiao, Howley, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20736/
https://ncbi.nlm.nih.gov/pubmed/9114003
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