Mitochondrial-Targeted Active Akt Protects SH-SY5Y Neuroblastoma Cells from Staurosporine-Induced Apoptotic Cell Death

Akt is a serine/threonine protein kinase that plays a vital role in promoting cellular survival. Predominantly cytosolic, upon stimulation with growth-factors or stress, active Akt translocates into mitochondria, but the functions of Akt in mitochondria are not yet fully understood. Mitochondria pla...

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Bibliografiske detaljer
Main Authors: Mookherjee, Paramita, Quintanilla, Rodrigo, Roh, Myoung-Sun, Zmijewska, Anna A., Jope, Richard S., Johnson, Gail V.W.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2072996/
https://ncbi.nlm.nih.gov/pubmed/17340627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21287
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