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Multivalent Interactions Between Lectins and Supramolecular Complexes: Galectin-1 and Self-Assembled Pseudopolyrotaxanes

Supramolecular chemistry has been employed to develop flexible and adaptable multivalent neoglycoconjugates for binding galectin-1 (Gal-1). Gal-1, a dimeric lectin with two galactoside-binding sites, regulates cancer progression and immune responses. Self-assembled pseudopolyrotaxanes comprised of l...

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Detalhes bibliográficos
Main Authors: Belitsky, Jason M., Nelson, Alshakim, Hernandez, Joseph D., Baum, Linda G., Stoddart, J. Fraser
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2072908/
https://ncbi.nlm.nih.gov/pubmed/17961826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2007.09.007
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