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RBM4 Interacts with an Intronic Element and Stimulates Tau Exon 10 Inclusion

Tau protein, which binds to and stabilizes microtubules, is critical for neuronal survival and function. In the human brain, tau pre-mRNA splicing is regulated to maintain a delicate balance of exon 10-containing and exon 10-skipping isoforms. Splicing mutations affecting tau exon 10 alternative spl...

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Bibliografiske detaljer
Main Authors: Kar, Amar, Havlioglu, Necat, Tarn, Woan-Yuh, Wu, Jane Y.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2072872/
https://ncbi.nlm.nih.gov/pubmed/16777844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M603971200
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