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Embryonic Exposure to Domoic Acid Increases the Susceptibility of Zebrafish Larvae to the Chemical Convulsant Pentylenetetrazole

BACKGROUND: Domoic acid (DA) is a neurotoxin produced by diatoms of the genus Pseudo-nitzschia that targets the limbic system to induce tonic–clonic seizures and memory impairment. In utero DA exposure of mice leads to a reduction in seizure threshold to subsequent DA exposures in mid-postnatal life...

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Autors principals: Tiedeken, Jessica A., Ramsdell, John S.
Format: Artigo
Idioma:Inglês
Publicat: National Institute of Environmental Health Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2072828/
https://ncbi.nlm.nih.gov/pubmed/18007982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.10344
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