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A dog model of fulminant hepatic failure produced by paracetamol administration.

Oral administration of graded doses of paracetamol to dogs produced hepatic necrosis with some similarities to the clinical syndrome seen in man following a paracetamol overdose. Coma, with raised levels of arterial ammonia, was produced and the aspartate aminotransferase levels became markedly elev...

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Bibliografske podrobnosti
Main Authors: Gazzard, B. G., Hughes, R. D., Mellon, P. J., Portmann, B., Williams, R.
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing|1 1975
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2072783/
https://ncbi.nlm.nih.gov/pubmed/1212424
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