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The induction of renal papillary necrosis in Gunn rats by analgesics and analgesic mixtures.

Homozygous members of the mutant Gunn strain of Wistar rats genetically lack the enzyme uridine diphosphate glucuronyl transferase. "High" and "low" dose gavage feeding for 18-34 days of an analgesic mixture containing aspirin, phenacetin and caffeine (APC) confirmed the previous...

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Détails bibliographiques
Auteur principal: Axelsen, R. A.
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing|1 1975
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2072714/
https://ncbi.nlm.nih.gov/pubmed/1203171
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