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Mutations in the Escherichia coli dnaG gene suggest coupling between DNA replication and chromosome partitioning.

Eleven conditional lethal dnaG(Ts) mutations were located by chemical cleavage of heteroduplexes formed between polymerase chain reaction-amplified DNAs from wild-type and mutant dnaG genes. This entailed end labeling one DNA strand of the heteroduplex, chemically modifying the strands with hydroxyl...

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Библиографические подробности
Главные авторы: Grompe, M, Versalovic, J, Koeuth, T, Lupski, J R
Формат: Artigo
Язык:Inglês
Опубликовано: 1991
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC207251/
https://ncbi.nlm.nih.gov/pubmed/1991720
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