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Inhibition by Lymphocyte Nuclei of DNA and RNA Synthesis in Stimulated Lymphocytes and Leukaemic Cells

Chromatin material in the form of intact bald lymphocyte nuclei was found to inhibit DNA and RNA synthesis in isologous cells previously stimulated with Phytohaemagglutinin (PHA) especially in 6 day cultures. These bald nuclear complexes produced a reduction in the DNA and RNA synthesis occurring in...

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Autori principali: Pegrum, G. D., Thompson, Elizabeth
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1971
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2072420/
https://ncbi.nlm.nih.gov/pubmed/5125269
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