Identification of three amino acid residues in the B subunit of Shiga toxin and Shiga-like toxin type II that are essential for holotoxin activity.

Shiga toxin of Shigella dysenteriae type I and Shiga-like toxins I and II (SLT-I and SLT-II, respectively) of enterohemorrhagic Escherichia coli are functionally similar protein cytotoxins. These toxin molecules have a bipartite molecular structure which consists of an enzymatically active A subunit...

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Veröffentlicht in:	J Bacteriol
Hauptverfasser:	Perera, L P, Samuel, J E, Holmes, R K, O'Brien, A D
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207236/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1991714/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.173.3.1151-1160.1991
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