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Reduced RNA polymerase II transcription in intact and permeabilized Cockayne syndrome group B cells

Cockayne syndrome (CS) is characterized by increased photosensitivity, growth retardation, and neurological and skeletal abnormalities. The recovery of RNA synthesis is abnormally delayed in CS cells after exposure to UV radiation. Gene-specific repair studies have shown a defect in the transcriptio...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Balajee, Adayabalam S., May, Alfred, Dianov, Grigory L., Friedberg, Errol C., Bohr, Vilhelm A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20718/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9113985/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.9.4306
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