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Effects of impromidine, a specific H2-receptor agonist and 2(2-pyridyl)-ethylamine, an H1-receptor agonist, on stimulation-induced release of [3H]-noradrenaline in guinea-pig isolated atria.

1 The specific histamine H2-receptor agonist, impromidine (3-100 nmol/l), increased the rate and force of beating of guinea-pig isolated atria. These effects were blocked by the H2-receptor antagonist, cimetidine (30 mumol/l), but not by the H1-receptor antagonist, mepyramine (0.1 mumol/l). 2 In atr...

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Bibliografiska uppgifter
Huvudupphovsmän: Rand, M. J., Story, D. F., Wong-Dusting, H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 1982
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071780/
https://ncbi.nlm.nih.gov/pubmed/6212093
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