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Distinction between the effects of barbiturates, benzodiazepines and phenytoin on responses to gamma-aminobutyric acid receptor activation and antagonism by bicuculline and picrotoxin.

1 Interactions of depressant and anticonvulsant drugs with the neuronal gamma-aminobutyric acid (GABA) receptor + effector system have been examined on afferent fibres to the rat cuneate nucleus in vitro. Three types of interaction have been measured: (a) potentiation of depolarizing responses to th...

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Detalles Bibliográficos
Autor Principal: Simmonds, M. A.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1981
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071690/
https://ncbi.nlm.nih.gov/pubmed/6265019
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