Dissociation constants of isoprenaline and orciprenaline and their relative efficacies on guinea-pig isolated atria determined by use of an irreversible beta-adrenoceptor antagonist.

1. Dissociation constant (KA) of isoprenaline and orciprenaline were determined for the positive inotropic and chronotropic responses of guinea-pig isolated atria. Cumulative dose-response curves to the agonists were constructed before and after incubation with and washout of the irreversible beta-a...

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Detalles Bibliográficos
Main Authors: Broadley, K. J., Nicholson, C. D.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1981
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071640/
https://ncbi.nlm.nih.gov/pubmed/6116509
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