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Antiarrhythmic effects of Org 6001 in rats: correlation with plasma and tissue drug concentrations.

The antiarrhythmic effects of Org 6001 following oral administration in the rat have been assessed and correlated with plasma, myocardial and skeletal muscle drug concentrations. Arrythmias were induced by coronary artery ligation in anaesthetized rats. Org 6001 (10, 20, 50 and 100 mg/kg given 1 h b...

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Bibliografiske detaljer
Main Authors: Kane, K., McDonald, F., Parratt, J., Timmer, C., Vink, J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1982
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071599/
https://ncbi.nlm.nih.gov/pubmed/7186821
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