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Evidence for an inhibitory presynaptic component of neuroleptic drug action.

1 The action of five neuroleptic drugs (haloperidol, cis-flupenthixol, chlorpromazine, fluphenazine and thioridazine) was studied on the synthesis and release of dopamine from rat striatal synaptosomes. 2. In vitro application of the drugs induced an inhibition of synthesis of [14C]-dopamine from L-...

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Detalhes bibliográficos
Main Authors: de Belleroche, J. S., Bradford, H. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071588/
https://ncbi.nlm.nih.gov/pubmed/6114766
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