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The existence of a new subtype of alpha-adrenoceptor on the rat anococcygeus is revealed by SGD 101/75 and phenoxybenzamine.

1 Noradrenaline and Sgd 101/75 (4(2-imidazoline-amino)-2-methylindazol-chlorhydrate) acted as full agonists in contracting the rat anococcygeus. 2 Very low concentrations of phenoxybenzamine (0.3 nM for 2-30 min) reduced preferentially the effects of Sgd 101/75. Preparations made insensitive to Sgd...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Coates, J., Jahn, U., Weetman, D. F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1982
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071563/
https://ncbi.nlm.nih.gov/pubmed/6121597
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