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Involvement of 5-hydroxytryptamine in the analgesic action of pethidine and morphine in mice.

1 Groups of mice were pretreated with the 5-hydroxytryptamine (5-HT) depletors, fenfluramine or p-chlorophenylalanine (PCPA), followed by pethidine or morphine. 2 Fenfluramine alone produced a short lasting analgesia but PCPA was without any effect. 3 Pethidine and morphine both increased hot plate...

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Detalhes bibliográficos
Main Authors: Botting, R., Morinan, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071530/
https://ncbi.nlm.nih.gov/pubmed/6175370
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