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Stereospecific dextrorphan tolerance in rats.
1 Levorphanol was 20 times more potent than dextrorphan in decreasing food-reinforced fixed ratio 15 responding in male Sprague Dawley rats. 2 Chronic dextrorphan (100 mg/kg, i.p.; every 8 h) resulted in the development of dextrorphan tolerance. The dextrorphan dose-effect curve was shifted to the r...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
1981
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2071512/ https://ncbi.nlm.nih.gov/pubmed/7214094 |
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