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Model of opiate dependence in the guinea-pig isolated ileum

1 Segments of ileum, incubated for 2-24 h at 22°C with normorphine (0.01 - 1.0 μM), in the presence of hexamethonium, contracted when challenged with naloxone (0.03 μM). No response to this dose of naloxone was induced either by incubation in control solution without opiate for 2-24 h or by exposure...

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Main Authors: Collier, Harry O.J., Cuthbert, Nigel J., Francis, David L.
格式: Artigo
語言:Inglês
出版: 1981
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071492/
https://ncbi.nlm.nih.gov/pubmed/7196786
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