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Uptake of 6-fluoro-5-hydroxytryptamine and 4,6-difluoro-5-hydroxytryptamine into releasable and non-releasable compartments of human platelets.
1 The ring-fluorinated compounds, 6-fluoro-5-hydroxytryptamine and 4,6-difluoro-5-hydroxytryptamine, are sterically similar to 5-hydroxytryptamine (5-HT) but have pKaS for their 5-hydroxyl groups (9.7 and 8.0 respectively) which are lower than that of 5-HT. 2 The rates at which [3H]-5-HT, [3H]-6-flu...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
1982
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2071466/ https://ncbi.nlm.nih.gov/pubmed/6896164 |
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