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Effects of folding on metalloprotein active sites

Experimental data for the unfolding of cytochrome c and azurin by guanidinium chloride (GuHCl) are used to construct free-energy diagrams for the folding of the oxidized and reduced proteins. With cytochrome c, the driving force for folding the reduced protein is larger than that for the oxidized fo...

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Autors principals: Winkler, Jay R., Wittung-Stafshede, Pernilla, Leckner, Johan, Malmström, Bo G., Gray, Harry B.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC20707/
https://ncbi.nlm.nih.gov/pubmed/9113974
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