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Mutations in DNA gyrase result in novobiocin resistance in halophilic archaebacteria.

We have developed a cloning vector for use in halophilic archaebacteria which has a novobiocin resistance determinant as a selectable marker. The resistance determinant, which was derived from the genome of a resistant mutant strain, was mapped to a site within a 6.7-kb DNA clone by using a recombin...

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Détails bibliographiques
Publié dans:J Bacteriol
Auteurs principaux: Holmes, M L, Dyall-Smith, M L
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207055/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1846146/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.173.2.642-648.1991
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