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Localization of a Class III Myosin to Filopodia Tips in Transfected HeLa Cells Requires an Actin-binding Site in its Tail Domain

Bass Myo3A, a class III myosin, was expressed in HeLa cells as a GFP fusion in order to study its cellular localization. GFP-Myo3A localized to the cytoplasm and to the tips of F-actin bundles in filopodia, a localization that is consistent with the observed concentration toward the distal ends of F...

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Publié dans:Mol Biol Cell
Auteurs principaux: Les Erickson, F., Corsa, Amoreena C., Dosé, Andréa C., Burnside, Beth
Format: Artigo
Langue:Inglês
Publié: American Society for Cell Biology 2003
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Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207009/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14517327/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E02-10-0656
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