Identification of the Shiga toxin A-subunit residues required for holotoxin assembly.

Recent X-ray crystallographic analyses have demonstrated that the receptor-binding (B) subunits of Shiga toxin (STX) are arranged as a doughnut-shaped pentamer. The C terminus of the enzymatic (A) subunit presumably penetrates the nonpolar pore of the STX B pentamer, and the holotoxin is stabilized...

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Bibliografische Detailangaben

Veröffentlicht in:	J Bacteriol
Hauptverfasser:	Haddad, J E, Jackson, M P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC206922/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8244934/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.175.23.7652-7657.1993
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