The tcmVI region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens encodes the tetracenomycin F1 monooxygenase, tetracenomycin F2 cyclase, and, most likely, a second cyclase.

Ítems similars

• Nucleotide sequence of the tcmII-tcmIV region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens and evidence that the tcmN gene encodes a multifunctional cyclase-dehydratase-O-methyl transferase.
  per: Summers, R G, et al.
  Publicat: (1992)
• Nucleotide sequences and heterologous expression of tcmG and tcmP, biosynthetic genes for tetracenomycin C in Streptomyces glaucescens.
  per: Decker, H, et al.
  Publicat: (1993)
• Isolation of tetracenomycin C-nonproducing Streptomyces glaucescens mutants.
  per: Motamedi, H, et al.
  Publicat: (1986)
• Anthracycline metabolites of tetracenomycin C-nonproducing Streptomyces glaucescens mutants.
  per: Yue, S, et al.
  Publicat: (1986)
• Sequence and transcriptional analysis of the Streptomyces glaucescens tcmAR tetracenomycin C resistance and repressor gene loci.
  per: Guilfoile, P G, et al.
  Publicat: (1992)