tRNA modification activity is necessary for Tet(M)-mediated tetracycline resistance.
Tet(M) protein interacts with the protein biosynthetic machinery to render this process resistant to the tetracycline in vivo and in vitro (V. Burdett, J. Biol. Chem. 266:2872-2877, 1991). To understand this process more completely, a mutant of Escherichia coli which is altered in the ability of Tet...
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| Published in: | J Bacteriol |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1993
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC206862/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8226667/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.175.22.7209-7215.1993 |
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